This is one of those full-page, full-color game ads I occasionally run across in the archives that personally rings no bells whatsoever:
It's The New Wave in 3-D VidGame Software! With 3-D Spritable Characters! And Full Spectrum Color Animation!
The Commodore 64 version reportedly never came out, and I'm suspicious about the Apple II version also. In fact, I haven't even been able to track down a copy of the IBM PC version, presumably the most successful SKU; a completely different Sega Genesis/Amiga game by the same name (aka Corporation) keeps throwing itself in the path of my furious Googling.
But I did track down an interesting interview with Pedersen Systems' chief developer and CEO, Roger Pedersen, over at gamedev.net. He developed and produced successful games for many other publishers, both before and after striking out (in both senses) with his own company, including a lot of successful GameTek and Acclaim titles. But when left to his own devices, he wrote an ad that might have meant something to game developers, but probably didn't do much for the general public, who may have thought Quick Manual Response meant it had an index.